Sinumedin Nasal Spray - 15ml

Sinumedin, (1.5 mg + 2.5 mg)/ml, nasal spray, solution

Mepyramini maleas + Phenylephrini hydrochloridum

Please read this leaflet carefully before taking this medicine because it contains: 

information important to the patient.

Always use this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist.

- Keep this leaflet so you can read it again if you need to.

- If you need advice or additional information, please ask your pharmacist.

- If you get any side effects, tell your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See point 4. 

- If you do not feel better or if you feel worse after 3 days, contact your doctor.

Table of contents of the leaflet

1. What Sinumedin is and what it is used for

2. Important information before using Sinumedin

3. How to use Sinumedin

4. Possible side effects

5. How to store Sinumedin

6. Package contents and other information

1. What Sinumedin is and what it is used for

Sinumedin contains two active substances: mepyramine maleate and phenylephrine hydrochloride. 

Mepyramine has antihistamine and antiallergic properties, and phenylephrine reduces mucosal congestion and clears the nose and openings of the paranasal sinuses. 

Additionally, the excipient cetalkonium chloride has antibacterial properties.

Sinumedin relieves a runny nose, clears the nose and the openings of the paranasal sinuses, facilitates breathing and has antibacterial properties.

Sinumedin is indicated for the treatment of:

- rhinitis (rhinitis) in inflammation of the nasal mucosa, including rhinitis occurring in case of

allergies (sensitivities); 

- sinusitis.

2. Important information before using Sinumedin

When not to use Sinumedin

- if you are allergic to the active substances or any of the other ingredients of the medicine (listed in section 6);

- in children under 6 years of age;

- during pregnancy and breastfeeding.

Warnings and precautions

Talk to your doctor or pharmacist before taking Sinumedin: 

- if you are a child;

- if you are elderly;

- if you suffer from allergic diseases (e.g. asthma) or dry rhinitis;

- if you have heart failure; 

- if you have high blood pressure;

- if you have diabetes;

- if you have pheochromocytoma;

- if you have hyperthyroidism;

- if you have an enlarged prostate gland;

- if you have narrow angle glaucoma;

- if you have been taking medicines to treat depression called monoamine oxidase inhibitors (selegiline, moclobemide, amiflamine), you should only use Sinumedin at least 14 days after stopping treatment with these medicines, unless your doctor tells you otherwise.

Kids 

Do not use in children under 6 years of age.

Sinumedin and other medicines 

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. 

If you are taking any of the medicines listed below, you may need to change them

dose or discontinuation of treatment:

- barbiturates, hypnotics and sedatives, atropine, tricyclic antidepressants (imipramine, opipramol, amitriptyline, doxepin, mianserin) - Sinumedin may intensify their effect;

- some beta-blockers, such as esmolol, may increase the effect of the phenylephrine component of Sinumedin, which may result in severe hypertension in some patients;

- monoamine oxidase inhibitors such as selegiline, moclobemide, amiflamine prolong and intensify the effect of Sinumedin.

Sinumedin with food, drink and alcohol

Sinumedin can be taken regardless of food or drink.

Sinumedin may enhance the effects of alcohol.

Pregnancy and breastfeeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to be pregnant 

child, ask your doctor for advice before taking this medicine.

Sinumedin must not be used during pregnancy and breastfeeding.

Driving and using machines

Sinumedin has minor or moderate influence on the ability to drive and use machines. Be careful.

Sinumedin contains methyl parahydroxybenzoate and propyl parahydroxybenzoate 

The medicine may cause allergic reactions (possibly delayed reactions). The drug may cause minor irritation to the skin, eyes and mucous membranes.

3. How to use Sinumedin

The drug is administered intranasally.

The recommended dose is